Associate Professor John Eden

Associate Professor John Eden

Gynaecologist and Reproductive Endocrinologist

Associate Professor John Eden established the Barbara Gross Research Unit in 1997 and has been its director ever since. He is also director of the Sydney Menopause Centre at the Royal Hospital for Women, Sydney, and a founding director of the Women’s Health and Research Institute of Australia. Having trained initially in Australia, he embarked on his research career in the UK at Charing Cross Hospital, London.  He became a fellow of the RANZCOG in 1988 and was amongst the first group of specialists to be accredited as a reproductive endocrinologist. John is Associate Professor of Reproductive Endocrinology at the University of New South Wales.  His research interests include managing menopause after breast cancer, polycystic ovary syndrome, osteoporosis, hormone replacement therapy as well as herbal medicine. He has authored over 100 scientific papers and has written two books.

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Publications in Major Journals from 2005

Eden J; O’Neill S, 2019, ‘The management of perimenopausal abnormal uterine bleeding’, Obstetrics, Gynaecology and Reproductive Medicine, http://dx.doi.org/10.1016/j.ogrm.2019.09.002

Eden J, 2017, ‘The endometrial and breast safety of menopausal hormone therapy containing micronised progesterone: A short review’, Australian and New Zealand Journal of Obstetrics and Gynaecology, vol. 57, pp. 12 – 15, http://dx.doi.org/10.1111/ajo.12583

O’Neill S; Eden J, 2017, ‘The pathophysiology of menopausal symptoms’, Obstetrics, Gynaecology and Reproductive Medicine, vol. 27, pp. 303 – 310, http://dx.doi.org/10.1016/j.ogrm.2017.07.002

Eden J; O’Neill S, 2017, ‘The management of perimenopausal menstrual symptoms’, Obstetrics, Gynaecology and Reproductive Medicine, vol. 27, pp. 120 – 124, http://dx.doi.org/10.1016/j.ogrm.2017.01.008

Golebiowski B; Badarudin N; Eden J; You JJ; Hampel U; Stapleton F, 2016, ‘Does endogenous serum oestrogen play a role in Meibomian gland disorder in postmenopausal women with dry eye?’, British Journal of Ophthalmology, vol. 101, pp. 218 – 222, http://dx.doi.org/10.1136/bjophthalmol-2016-308473

Golebiowski B; Badarudin N; Eden J; Liu J; Gerrand L; Robinson J; Hampel U; You J; Stapleton F, 2016, ‘The effects of transdermal testosterone and oestrogen therapy on dry eye in post-menopausal women: a randomised, placebo-controlled, pilot study’, British Journal of Ophthalmology, vol. 101, pp. 926 – 932, http://dx.doi.org/10.1136/bjophthalmol-2016-309498

Eden J, 2016, ‘Managing menopausal symptoms after breast cancer’, European Journal of Endocrinology, vol. 174, pp. R71 – R77, http://dx.doi.org/10.1530/EJE-15-0814

Strezova A; O’Neill S; O’Callaghan C; Perry A; Liu J; Eden J, 2016, ‘Cultural issues in menopause: An exploratory qualitative study of Macedonian women in Australia’, Menopause, vol. 24, pp. 308 – 315, http://dx.doi.org/10.1097/GME.0000000000000750

Eden JA, 2015, ‘DHEA replacement for postmenopausal women: Placebo or panacea?’, Climacteric, vol. 18, pp. 439 – 440, http://dx.doi.org/10.3109/13697137.2015.1017706

Eden J; O’Neill S, 2014, ‘The management of perimenopausal menstrual symptoms’, Obstetrics, Gynaecology and Reproductive Medicine, vol. 24, pp. 233 – 237, http://dx.doi.org/10.1016/j.ogrm.2014.05.004

O’Neill S; Eden J, 2014, ‘The pathophysiology of menopausal symptoms’, Obstetrics, Gynaecology and Reproductive Medicine, vol. 24, pp. 349 – 356, http://dx.doi.org/10.1016/j.ogrm.2014.10.006

Eden J, 2013, ‘Vitex agnus-castus and premenstrual syndrome’, Medicine Today, vol. 14, pp. 71 – 72

Eden J, 2013, ‘A new mother with night sweats: Commentary’, Medicine Today, vol. 14, pp. 67 – 68

Eden JA, 2013, ‘Menopausal status, adipose tissue, and breast cancer risk: Impact of estrogen replacement therapy’, Hormone Molecular Biology and Clinical Investigation, vol. 14, pp. 57 – 63, http://dx.doi.org/10.1515/hmbci-2013-0007

Lethaby A; Marjoribanks J; Kronenberg F; Roberts H; Eden J; Brown J, 2013, ‘Phytoestrogens for menopausal vasomotor symptoms’, Cochrane Database of Systematic Reviews, vol. 2013, http://dx.doi.org/10.1002/14651858.CD001395.pub4

O’Neill S; Eden JA, 2012, ‘The pathophysiology of menopausal symptoms’, Obstetrics Gynaecology and Reproductive Medicine, vol. 22, pp. 63 – 69, http://dx.doi.org/10.1016/j.ogrm.2011.12.006

Eden JA, 2012, ‘Phytoestrogens for menopausal symptoms: A review’, Maturitas, vol. 72, pp. 157 – 159, http://dx.doi.org/10.1016/j.maturitas.2012.03.006

Eden JA; O’Neill S, 2012, ‘The management of perimenopausal menstrual symptoms’, Obstetrics Gynaecology and Reproductive Medicine, vol. 22, pp. 98 – 101, http://dx.doi.org/10.1016/j.ogrm.2012.01.001

Eden JA, 2011, ‘Breast cancer, stem cells and sex hormones. Part 3: The impact of the menopause and hormone replacement’, Maturitas, vol. 68, pp. 129 – 136, http://dx.doi.org/10.1016/j.maturitas.2010.11.005

Panay N, Al-Azzawi F, Bouchard C, Davis SR, Eden A et al. Testosterone treatment of HSDD in naturally menopausal women: the ADORE study. Climacteric 2010; 13: 121-31.

Panay N; Al-azzawi F; Bouchard C; Davis SR; Eden JA; Lohdi I; Rees M; Rodenberg C; Rymer J; Schwenkhagen A; Sturdee D, 2010, ‘Testosterone treatment of HSDD in naturally menopausal women: the ADORE study’, Climacteric, vol. 13, pp. 121 – 131, http://dx.doi.org/10.3109/13697131003675922

Eden JA, 2010, ‘Breast cancer, stem cells and sex hormones Part 1. The impact of fetal life and infancy’, Maturitas, vol. 67, pp. 117 – 120, http://dx.doi.org/10.1016/j.maturitas.2010.05.005

Eden J, 2010, ‘Does mammography reduce breast cancer mortality?’, Climacteric, vol. 13, pp. 400 – 401, http://dx.doi.org/10.3109/13697137.2010.493123

Eden JA, 2010, ‘Human breast cancer stem cells and sex hormones – a narrative review’, Menopause – the Journal of the North American Menopause Society, vol. 17, pp. 801 – 810, http://dx.doi.org/10.1097/gme.0b013e3181d3cdd7

Eden JA, 2010, ‘Breast cancer, stem cells and sex hormones. Part 2: The impact of the reproductive years and pregnancy’, Maturitas, vol. 67, pp. 215 – 218, http://dx.doi.org/10.1016/j.maturitas.2010.07.012

Eden JA, 2010, ‘Why does oestrogen-only hormone therapy have such a small impact on breast cancer risk? A hypothesis’, Gynecological Endocrinology, vol. 27, pp. 1 – 6, http://dx.doi.org/10.3109/09513590.2010.488778

Liu J; Eden JA, 2008, ‘The menopausal experience of Greek women living in Sydney’, Menopause – the Journal of the North American Menopause Society, vol. 15, pp. 476 – 481, http://dx.doi.org/10.1097/gme.0b013e318154bda0

Liu J, Eden J. The experience of menopausal symptoms by Arabic women in Sydney. Climacteric 2007; 10:72-79

Liu J, Eden J. Experience and Attitudes toward Menopause in Chinese Women Living in Sydney – A Cross Sectional Survey. Maturitas 2007; 58(4):359-365.

Eden JA. Tibolone for postmenopausal women. O and G magazine 2007; 9:13-14.

Hafiz I. Liu J, Eden J. A quantitative analysis of the menopause experience of Indian women living in Sydney. Australian and New Zealand Journal of Obstetrics and Gynaecology 2007; 47(4):329-334.

El-Hage G, Manga RZ, Eden JA. A double-blind, placebo-controlled trial of the effect of testosterone cream on the sexual motivation of menopausal hysterectomised women with hypoactive sexual desire disorder. Climacteric 2007; 10: 335-343.

Costello MF, Shrestha B, Eden J, Johnson, Sjoblom P. Metformin versus oral contraceptive pill in polycystic ovary syndrome: a Cochrane review. Human Reproduction 2007; 22(5):1200-1209.

Eden JA, Hacker NF, Fortune M. Three cases of endometrial cancer associated with bioidentical hormone replacement therapy. Medical Journal of Australia 2007; 187 (4): 240-1

Peeyananjarassri K, Cheewadhanaraks S, Hubbard M, Manga RZ, Manocha R, Eden J. Menopause symptoms in a hospital-based sample of women in southern Thailand. Climacteric 2006; 9:23-29.

Eden J. The need for tissue selective menopausal agents. Gynecological Endocrinology 2005; 21(Supplement 1):22-27.

Yaffe M, Hendrix S, Pike M, Santen R, Eden J Genazzani A. Is mammographic density as currently measured, a robust surrogate marker for breast cancer? Gynecological Endocrinology 2005; 21 (supplement 1): 17-21

Books

Womens Hormone Problems, an 80 page book for undergraduates and general practitioners. (Three editions – 48,000 sold).

PCOS – a woman’s guide to identifying and managing PCOS. Allen and Unwin. 2005

True Lies – Getting over past hurts. How to let go of emotional pain before it eats you alive! Self published available at WHRIA.

Chapters in Books

Eden JA (1991). Dysmenorrhea and Premenstrual Syndrome. In, Essentials of Obstetrics and Gynecology, Vol 2 (Hacker & Moore eds), WB Saunders Co, Philadelphia.

Eden JA.  Hirsutism. In, Progress in Obstetrics and Gynaecology (Ed Studd JWW) 1991 (9), Churchill Livingstone, London, 319-34.

Eden JA. Androgenic disorders and the Menopause. The Clinical Management of Sex Hormone Deficiency: Eds Wren BG, Nachitgall L. McGraw Hill, Sydney 1996, 32-40.

Eden JA. Hormone replacement therapy and cancer. The Clinical Management of Sex Hormone Deficiency: Eds Wren BG, Nachitgall L. McGraw Hill, Sydney 1996, 126-133.

Eden JA. Hormone replacement therapy and breast cancer. The Clinical Management of Sex Hormone Deficiency: Eds Wren BG, Nachitgall L. McGraw Hill, Sydney 1996, 134-140.

Eden JA (1995). The use of hormone replacement therapy in women previously treated for breast cancer. Contemporary Reviews in Obstetrics and Gynaecology (Eds Chamberlain G, Drife J). Parthenon Publishers. Volume 7, 20-24.

Eden JA. Gynaecological Endocrinology. Handbook of Obstetrics and Gynaecology, 4th edition (Eds Leader LR, Bennett MJ, Wong F). Chapman and Hall Medical, Melbourne, 1996, 361-382.

Eden JA (1996). Hormone Replacement after breast cancer. American Society of Clinical Oncology Educational Book, Bostrom Corporation, 187-9.

Eden JA. Hormone replacement therapy after breast cancer. Progress in Reproductive Medicine (Eds Studd J, Asch R), Parthenon Publishers.

Eden JA (1996). Polycystic ovary syndrome. Surgical Pathology of the Ovaries. Second Edition. (Eds Russell P, Farnsworth A), Churchill Livingstone Publishers.

Eden J. Therapeutics – cancer of the reproductive organs. Breast. Oestrogen and Progestogens in Clinical Practice. First edition. Churchill Livingstone Publishers.

Eden JA (1998). Phytoestrogens and the Menopause. In, Phytoestrogens (Ed Adlercreutz H.), Bailliere’s Clinical Endocrinology and Metabolism, 581-8.

Prescribing HRT in the presence of known gynaecological problems. In, Current opinion on the management of the menopause.

Management of menopausal symptoms after breast cancer (2000). Management of the Menopause in the Millennium. (Ed JWW Studd), Parthenon Publishing, 221-4.

Menopause. In, General Practice: the integrative approach. Phelps and Hassed, Elsevier press 2010

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